Prenatal testing is a significant field of human genetic diagnostics.

Our excellent technology and quality of interpretation ensures reliable, quick and high-sensitivity testing both for prenatal diagnostics and all other diagnostic disciplines.

In prenatal testing it may be considered expedient, as in postnatal testing, to select a gene panel on the basis of the clinical picture. Using a Whole Exome Sequencing (WES)-based approach, data interpretation can be extended into a complete WES analysis in case of initially evaluated and inconspicuous panel findings, and data evaluation according to differential diagnostic aspects can be enabled.

However, for complex, non-specific disorders in which a more specific selection of genes in the form of a gene panel is not considered expedient, a full WES analysis may be a useful primary approach.

Depending on the suspected clinical disorder we offer our full test range in prenatal diagnostics including single-gene testing, gene-panel testing and WES analyses. Our experts in human genetics are available to answer any questions you may have and provide prenatal clinical genetics service.

Through our highly experienced Limbach Genetics laboratories, we also offer non-invasive prenatal testing (NIPT), array CGH, as well as cytogenetic testing and other methods relevant in the field of prenatal diagnostics. 

Features and benefits of our diagnostic services:

• State-of-the-art equipment
• Customised gene panels designed by experts with many years of experience and excellent Knowledge - no product off the rack
• Our analyses are always up to date and include all known causative variants of a disease
• Carefully selected, expert-reviewed evaluation algorithms that ensure high-sensitivity results and a detailed interpretation of the causative variants
• Duplicate evaluation and interpretation of the complex data through our interdisciplinary, highly experienced team of scientists and physicians specialising in human genetics that ensure excellent reliability and quality
• Quick turnaround times for prenatal and other time-critical tests, depending on the complexity of the respective test method
• Clearly structured, conclusive and concise reports

Preanalytics

Please use express shipping for prenatal samples. Please inform us in advance to ensure prompt handling of samples upon receipt. Cultivation of fetal material is presently not available, but will be included in our services soon.

Therefore, please make sure to submit isolated fetal DNA or sufficient volumes of native material.

Important: When submitting prenatal test requests, please include 3-5 mL of EDTA blood collected from the mother in the shipment to help us rule out maternal cell contamination.

Please contact us if you have any questions.